HIV-1 Replication Inhibited by Engineered Human Fusion Protein

September 13, 2009 by admin 

In 2004, Jeremy Luban and colleagues from the University of Geneva, Switzerland, reported that New World owl monkeys (Aotus genus) make a fusion protein – AoT5Cyp – that potently blocks HIV-1 infection. The human genome encodes the equivalent of the 2 components of AoT5Cyp (i.e., TRIM5 and cyclophilin A), but humans unfortunately do not make the T5Cyp fusion protein. In their new study in the Journal of Clinical Investigation, Luban et al.

Source: HIV-1 Replication Inhibited by Engineered Human Fusion Protein

Comments

Feel free to leave a comment...
and oh, if you want a pic to show with your comment, go get a gravatar!





Security Code: