Hemophilias Treatment Information

November 2, 2009 by admin 

Hemophilias are a group of disorders, which are among the most common and serious inherited bleeding disorders. Hemophilia is actually a collection of several different genetic disorders passed on by heredity. The two most common types are hemophilia A and hemophilia B. Hemophilia generally affects men. In fact, one third of 10000 men is born with hemophilia A. About 17000 Americans are born with the genetic disease that causes the disease. Globally, an estimated 500000 people are living with a form of hemophilia.

Hemophilia A is responsible for eighty percent of all cases. The genetic abnormalities responsible for hemophilia Following the weakness or abnormal production of the protein coagulation factor VIII. Hemophilia B, the second most common form of hemophilia, Factor IX affects proteins and represents nearly twenty percent of cases of hemophilia. Other heredity-based hemophilia disorders may affect other blood clotting factors, but they occur rarely. The most common and major complication of hemophilia is chronic hemarthroses which can lead to joint destruction. The other most common complication is infections transmitted by therapy.

These include hepatitis B, hepatitis C, hepatitis A, HIV, HPV and parvovirus B19. The treatment can prevent crippling deformities and prolong life expectancy. The replacement may be necessary, even for a minor surgery, such as tooth extraction. In addition, aminocaproic acid is commonly used for oral bleeding to inhibit the activity fibrinolytic system present in the oral mucosa. Préventives treatment the patient learns how to prevent injuries, manage minor bleeding, and recognize the bleeding. Patients should avoid aspirin, medicines containing aspirin, NSAIDs, as they may increase bleeding. Genetic counseling should be sought.

Hemophilias Treatment and Prevention Tips

1. Gene therapy is useful treatment of this condition.

2. Aminocaproic acid is commonly used for oral bleeding.

3. Plasmapheresis may help reduce the antibody load in those patients.

4. Avoid aspirin, aspirin containing drugs, and NSAI Drugs.

5. Education needs to be provided to the patient caregiver about need for early treatment.

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